The amino acids glutamine and glutamic acid are closely related in a chemical sense. The human body is able to produce L-glutamine itself, from L-glutamic acid through the glutamate ammonium ligase. Considering the numerous metabolic processes glutamine is a part of, it is not surprising that it is the amino acid with the highest concentration in blood plasma, musculature and cerebral and spinal fluid. At 60%, it represents the largest amount of free amino acids in the body.
The demand for glutamine increases with physical and mental stress. Production of this important amino acid, which takes place in the body, often slows down with age and does not generate sufficient amounts. External supplementation is recommended in such cases.